使君子 發表於 2010-1-17 13:14:27

两篇极好的基因论文

<br><div><br></div><div><br></div><div><span class="Apple-style-span" style="color: rgb(68, 68, 68); font-family: Verdana, Helvetica, Arial, sans-serif; font-size: 12px; border-collapse: collapse; line-height: 19px; "><div id="threadtitle" style="word-wrap: break-word; line-height: normal; margin-bottom: 8px; border-bottom-width: 1px; border-bottom-style: dashed; border-bottom-color: rgb(230, 231, 225); "><h1 style="word-wrap: break-word; margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; font-size: 1.17em; line-height: normal; ">珠江三角洲汉族人群的亚群分析</h1></div><div class="t_msgfontfix" style="word-wrap: break-word; line-height: normal; min-height: 100px; "><table cellspacing="0" cellpadding="0" style="word-wrap: break-word; empty-cells: show; border-collapse: collapse; line-height: normal; width: 600px; table-layout: fixed; margin-left: 1px; "><tbody style="word-wrap: break-word; line-height: normal; "><tr style="word-wrap: break-word; line-height: normal; "><td class="t_msgfont" id="postmessage_188" style="word-wrap: break-word; color: rgb(68, 68, 68); font: normal normal normal 12px/1.6em Verdana, Helvetica, Arial, sans-serif; line-height: 1.6em; font-size: 14px; "><font color="#000000" style="word-wrap: break-word; line-height: normal; "><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><br>遗传</font><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">&nbsp; &nbsp; 2003 25 (6): 645-648&nbsp; &nbsp;&nbsp;<br></font></font><br style="word-wrap: break-word; line-height: normal; "><strong style="word-wrap: break-word; text-align: left; font-style: normal; line-height: normal; font-weight: bold; "><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 13.5pt; "><span href="tag.php?name=%BA%BA%D7%E5" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; line-height: normal; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); white-space: nowrap; ">珠江三角洲汉族</span>人群的亚群分析<br></font></font></strong><br style="word-wrap: break-word; line-height: normal; "><font color="#000000" style="word-wrap: break-word; line-height: normal; "><font face="宋体 " style="word-wrap: break-word; line-height: normal; ">吕德坚</font><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">,</font><font face="宋体 " style="word-wrap: break-word; line-height: normal; ">刘秋玲</font><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">,</font><font face="宋体 " style="word-wrap: break-word; line-height: normal; ">陆惠玲</font></font><br style="word-wrap: break-word; line-height: normal; "><font color="black" style="word-wrap: break-word; line-height: normal; "><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><br>中山大学中山医学院法医物证教研室,广州</font></font><br style="word-wrap: break-word; line-height: normal; "><font color="#000000" style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><strong style="word-wrap: break-word; text-align: left; font-style: normal; line-height: normal; font-weight: bold; "><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><br>摘要</font></strong></font><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">&nbsp;&nbsp;</font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">为调查珠江三角洲地区汉族人群中是否存在着亚群结构,对来自广州、佛山、东莞、江门和中山</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">-</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">珠海</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">5</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">个不同地区的</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">471</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">随机个体血样本进行</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">15</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">个</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; "><span href="tag.php?name=STR" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; line-height: normal; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); white-space: nowrap; ">STR</span></font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">的基因分型,并作</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">Hardy-Weinberg</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">平衡检验,比较群体之间的等位基因频率,计算这个</font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; ">5</font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">个地区人群间的共祖系数。结果显示,<b><font class="Apple-style-span" color="#0000FF">珠江三角洲汉族人群</font></b></font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><b><font class="Apple-style-span" color="#0000FF">之间的共祖系数小于</font></b></font></font><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; "><font face="Times New Roman " style="word-wrap: break-word; line-height: normal; "><b><font class="Apple-style-span" color="#0000FF">0.01</font></b></font></font><font face="宋体 " style="word-wrap: break-word; line-height: normal; "><font style="word-wrap: break-word; line-height: normal; font-size: 9pt; ">。因此,珠江三角洲地区汉族人群中没有明显的亚群结构。<br></font></font></font><br style="word-wrap: break-word; line-height: normal; "><div style="text-align: left;"><font class="Apple-style-span" color="#000000" face="宋体" size="3"><span class="Apple-style-span" style="font-size: 12px;"><b><br></b></span></font></div><font class="Apple-style-span" color="#535353" face="Arial, Helvetica, sans-serif"><span class="Apple-style-span" style="border-collapse: separate;"><font class="Apple-style-span" color="#800080" face="宋体"><span class="Apple-style-span" style="border-collapse: collapse;"><br></span></font></span></font></td></tr></tbody></table></div></span></div><div><br></div><div><br></div><div><br></div><div><span class="Apple-style-span" style="color: rgb(68, 68, 68); font-family: Verdana, Helvetica, Arial, sans-serif; font-size: 12px; border-collapse: collapse; line-height: 19px; "><div id="threadtitle" style="word-wrap: break-word; line-height: normal; margin-bottom: 8px; border-bottom-width: 1px; border-bottom-style: dashed; border-bottom-color: rgb(230, 231, 225); "><h1 style="word-wrap: break-word; margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; font-size: 1.17em; line-height: normal; ">邕宁汉族与周边民族的群体差异分析</h1></div><div class="t_msgfontfix" style="word-wrap: break-word; line-height: normal; min-height: 100px; "><table cellspacing="0" cellpadding="0" style="word-wrap: break-word; empty-cells: show; border-collapse: collapse; line-height: normal; width: 600px; table-layout: fixed; margin-left: 1px; "><tbody style="word-wrap: break-word; line-height: normal; "><tr style="word-wrap: break-word; line-height: normal; "><td class="t_msgfont" id="postmessage_2019" style="word-wrap: break-word; color: rgb(68, 68, 68); font: normal normal normal 12px/1.6em Verdana, Helvetica, Arial, sans-serif; line-height: 1.6em; font-size: 14px; "><br>国际<span href="tag.php?name=%D2%C5%B4%AB%D1%A7" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; line-height: normal; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); white-space: nowrap; ">遗传学</span>杂志 &gt; 2008年6期&nbsp;<br style="word-wrap: break-word; line-height: normal; "><br><span href="tag.php?name=%BA%BA%D7%E5" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); "><span class="Apple-style-span" style="line-height: 22px;">邕宁</span></span><span href="tag.php?name=%BA%BA%D7%E5" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; line-height: normal; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); white-space: nowrap; ">汉族</span>与周边民族的群体差异分析<br style="word-wrap: break-word; line-height: normal; "><br>唐剑频 于昕 蒋丰慧 于晓军<br style="word-wrap: break-word; line-height: normal; "><br style="word-wrap: break-word; line-height: normal; ">目的:获取15个<span href="tag.php?name=STR" onclick="tagshow(event)" class="t_tag" style="word-wrap: break-word; line-height: normal; cursor: pointer; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(255, 0, 0); white-space: nowrap; ">STR</span>基因座在邕宁地区汉族的群体遗传学和法医学数据,并分析邕宁汉族群体与周边民族群体的遗传关系.<br>方法:利用复合扩增技术,对15个STR基因座进行基因型分型.Arlequin 3.1软件分析群体间遗传差异和遗传距离,用邻接法构建12个群体的系统树.<br>结果:15个STR基因座的多态信息量(polymorphic information content,PIC)为0.51~0.84,观察杂合度为0.59~0.88,期望杂合度为0.54~0.89,个人识别率(discrimination power,DP)为0.77~0.96,非父排除率(probability of exclusion,PE)为0.24~0.77.在TH01基因座,邕宁汉族群体与回族、京族的群体间非差异exact P值均大于0.05.<br>结论:在邕宁汉族与回族、京族之间,TH01基因座的等位基因频率分布无差异.广西各民族间存在着深远的基因交流,具有很高的相同血缘,其中<b><font class="Apple-style-span" color="#0000FF">邕宁汉族与壮族、侗族遗传距离最近.</font></b><br style="word-wrap: break-word; line-height: normal; "><br style="word-wrap: break-word; line-height: normal; "><br></td></tr></tbody></table></div></span></div><div><br></div><div><br></div><div><br></div><div><br></div>

使君子 發表於 2010-1-17 13:21:00

<span class="Apple-style-span" style="font-size: large;"><div><span class="Apple-style-span" style="font-size: large;"><br></span></div><div><span class="Apple-style-span" style="font-size: large;"><br></span></div>「共祖系数」低到几乎为零,说明大多数「族谱」都是攀附伪造。在清代的珠江三角洲,小族「并入」大族,大族又伪造「南迁」族谱,比比皆是。攀附伪造「族谱」现象,在越南朝鲜日本都很普遍。</span><div><span class="Apple-style-span" style="font-size: large;"><br></span></div><div><span class="Apple-style-span" style="font-size: large;"><br></span></div>

zgldrpgq 發表於 2010-2-2 11:05:19

kei

朋友,古越族已经消失在历史长河里了,假如你还对故国充满感情,去越南去吧,据说那里的京族还是古越族后代,去吧,去找组织吧我可怜的孩子

华广 發表於 2010-2-7 01:58:59

我估计我哋粤人应该得两到三成左右嘅人系汉人南下嘅产物!<IMG border=0 alt="" src="http://bbs.cantonese.asia/images/smilies/default/sweat.gif" smilieid="10">

潮裔 發表於 2010-2-7 22:50:27

如果一个越南人同一个广东人企埋一齐,根本分唔清边个系越南人,边个系广东人。但一个外省人同广东人反而比较容易分别出。

使君子 發表於 2010-2-17 15:48:50

[贺岁帖]新鲜滚热辣的人类学数据


今个本命年,我会过得安乐,事关得知原来两位分子人类学界强人台柱 百粤人、兰海 都是我粤血统,也得知僚人的Y染色体保存完好,没有怎么受到北来人种的侵扰。



http://konglong.5d6d.com/thread-7656-1-1.html

兰海出生于柳州,身份证户口簿写着「汉族」,「家谱」写着「宋朝北人南迁」,长相与一般僚人无异,他的Y染色体单倍型检测结果是D1,是正宗的粤地土著,「家谱」上面记载的什么「北人南迁」完全可以当废品烧掉。



http://konglong.5d6d.com/thread-7650-1-1.html

百粤人是祖籍云浮的艾人(也就是所谓的「客家」),他的Y染色体单倍型检测结果是O3a4。用他本人的话来讲,O3a4是由珠江流域上游的黔滇向长江流域和东南沿海扩散,也是土著男性的单倍型。




http://konglong.5d6d.com/redirect.php?tid=6895&goto=lastpost#lastpost

僚人Y染色体单倍型的结果公布了。O2a是僚人第一大单倍型(与东南亚西部各族完全一致),占到三程;O*是第二大,占两程几;再合计上O1、C、D、K等小兄弟,「北人南迁」歪理邪说彻底破产了。

xinmeigan 發表於 2010-3-17 09:19:50

别断章取义,D在北方更多吧.
还有,没有共祖现象正好说明,我们的祖先来自五湖四海,要不你到广西壮族区测测,肯定同源性很高。
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